Adrenergic Receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline). Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. High levels of circulating epinephrine cause vasoconstriction. At lower levels of circulating epinephrine, β-adrenoreceptor stimulation dominates, producing vasodilation followed by decrease of peripheral vascular resistance.
Many cells possess these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system. The sympathetic nervous system is responsible for the fight-or-flight response, which includes dilating the pupils, increasing heart rate, mobilizing energy, and diverting blood flow from non-essential organs to skeletal muscle.
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Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.
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Clorprenaline HCl is a β2-receptor agonist, it has a significant expansion of the bronchial effect.
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Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.
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Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.
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Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity.
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Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.
More
-
Clorprenaline HCl is a β2-receptor agonist, it has a significant expansion of the bronchial effect.
More
-
Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.
More
-
Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.
More
-
Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity.
More
